The major histocompatibility complex region and diversity of the local chicken populations in Niger
Authors
Date Issued
2023-12Date Online
2023-12Language
enType
Journal ArticleReview status
Peer ReviewISI journal
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Open AccessUsage rights
CC-BY-4.0Metadata
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Hassan Ousseini, M., Machuka, E., Kyallo, M., Tiambo, C.K., Domelevo Entfellner, J.-B. and Pelle, R. 2023. The major histocompatibility complex region and diversity of the local chicken populations in Niger. Journal of World’s Poultry Science 2(4): 47–54.
Permanent link to cite or share this item: https://hdl.handle.net/10568/136086
Abstract/Description
Introduction: The major histocompatibility complex (MHC) of chicken is highly polymorphic, and it is linked to several disease resistance or susceptibility traits. Therefore, the current study aimed to analyze the genetic diversity in the MHC region of Nigerien local chicken (Dourgou, Goggori, Kolonto, Tchagara, Gouzou-gouzou, and Popular) using a high polymorphic microsatellite marker named LEI0258 to determine the diversity of chickens kept at the four agroecological zones in Niger.
Materials and methods: A total of 601 chickens from six local Nigerien chickens were sampled. By capillary electrophoresis using LEI0258 marker, 403 samples with different fragment sizes were randomly chosen and sequenced.
Results: The findings indicated 80 different alleles ranging in size from 181 to 474 bp. A total of 22 new alleles and 39 private alleles (that existed in only one breed) were detected. The alleles 309, 295, and 193 were the most predominant in the Nigerien local chicken population. Nine polymorphisms were observed along the LEI0258 sequence, including three in the upstream (one indel and two Single Nucleotide Polymorphism [SNP]), one in the repeat region at the last R12 (SNP), and five in the downstream (two indels and three SNPs).
Conclusion: The chickens are not clustering according to their agroecological zone of origin. They are randomly distributed across the four investigated agroecological zones. The information found in this study is invaluable in breeding and conservation programs associated with several disease resistance or susceptibility traits.
CGIAR Author ORCID iDs
Christian Keambou Tiambohttps://orcid.org/0000-0002-7401-753X
Jean-Baka Domelevo Entfellnerhttps://orcid.org/0000-0002-8282-1325
Roger Pellehttps://orcid.org/0000-0003-1053-085X
AGROVOC Keywords
Subjects
ANIMAL BREEDING; CHICKENS; GENETICS; INDIGENOUS BREEDS;Countries
NigerOrganizations Affiliated to the Authors
University Dan Dicko Dankoulodo of Maradi; International Livestock Research InstituteInvestors/sponsors
Africa Biosciences Challenge Fund; Department for Foreign Affairs and Trade, Australia; Syngenta Foundation for Sustainable Agriculture; Bill & Melinda Gates Foundation; Foreign, Commonwealth and Development Office, United Kingdom; Swedish International Development Cooperation AgencyCollections
- ILRI articles in journals [6834]
- ILRI BecA articles [282]
- ILRI livestock genetics program outputs [914]